Preservative tBHQ
New research in part funded by CRIS, now live in Frontiers Immunology, discusses the preservative ingredient tBHQ. In this post, we look at tBHQ and its impact on immune systems.
Research
Working Group: Identification and Validation of Cell-based Assays for Developmental Immunotoxicity Testing
Overview:
It is increasingly clear that the global rise in inflammatory diseases and immune-mediated disorders can be traced back to early development.
The International Working Group on Alternatives to in vivo Developmental Immunotoxicity (DIT) Testing is working to identify and validate new models…
Glyphosate & Aspartame
Social listening allows us to see public thoughts, trends, and sentiments around specific ingredients. In this report, we look at glyphosate and aspartame.
Establishment of a point of departure for CBD hepatotoxicity employing human HepaRG spheroid
Abstract: The United States Food and Drug Administration recently approved the use of Cannabis sativa derived cannabidiol (CBD) in the treatment of Dravet Syndrome and Lennox-Gastaut Syndrome, under the trade name, Epidiolex. In double-blinded, placebo-controlled clinical trials, elevated ALT levels were observed…
The protective effect of butylated hydroxytoluene and 3-hydroxytyrosol on food allergy in mice
Title: The protective effect of butylated hydroxytoluene and 3-hydroxytyrosol on food allergy in mice
Abstract:
Objective -To test the effect of two dietary antioxidants: butylated hydroxytoluene (BHT) and 3- hydroxytyrosol (3-HT) in experimental food allergy.
Methods - BALB/c mice maintained on control diet or diet…
Lead and the Developing Immune System Study
Evaluation of a human developmental immunotoxicity assay.
Background:
Lead exposure is a long-term burden on communities in the United States, due to environmental pollution, past utilization of lead-based paint in homes, and aging infrastructure, with a disproportionate amount of the burden falling upon…
Cannabidiol selectively modulates interleukin (IL)-1β and IL-6 production in toll-like receptor activated human peripheral blood monocytes
Abstract: Cannabidiol (CBD) is a major non-euphoric cannabis-derived compound that has become popular in its over-the-counter use. CBD possesses low affinity for cannabinoid receptors, while the primary molecular target(s) by which it mediates biological activity remain poorly defined. Individuals commonly self-medicate using…
The current understanding of the benefits, safety, and regulation of cannabidiol in consumer products
Abstract: The popularity of cannabidiol (CBD) in consumer products is soaring as consumers are using CBD for general health and well-being as well as to seek relief from ailments especially pain, inflammation, anxiety, depression, and sleep disorders. However, there are limited data…
Academic Journal Publication – Evaluation of immunologic and intestinal effects in rats administered an E 171-containing diet, a food grade titanium dioxide (TiO2)
Abstract:
The toxicity of dietary E 171, a food grade titanium dioxide was evaluated. A recent study reported rats receiving E 171 in water developed inflammation and aberrant crypt foci (ACF) in the gastrointestinal tract. Here, rats received food containing E 171…
Plastics, Microplastics, & Nanoplastics
Social listening allows us to see public thoughts, trends, and sentiments around specific ingredients. In these reports, we explore public sentiments, concerns, conversations, and more around plastics, microplastics, and nanoplastics.